What is semaglutide?
Semaglutide is a GLP1 receptor agonist. GLP1 is an incretin hormone that increases insulin and decreases glucagon (the hormone that signals hunger), which decreases blood sugar. Gastric emptying is also delayed, causing signals to be sent to the brain that the stomach is full.
Semaglutide is indicated for:
- Controlling blood sugar in type 2 diabetes
- Reducing stroke, heart attack, and death in patients with type 2 diabetes and known heart disease
- Weight loss
What are the side effects of semaglutide?
The most common side effects of semaglutide are GI related.
- nausea
- vomiting
- diarrhea
- constipation
- headaches
How should I treat my side effects?
While the GI side effects tend to lessen over time with longer use of semaglutide, these are some effective recommendations people have used to treat side effects if they occur.
Nausea/Vomiting
Non-medication related tips:
- Eating smaller meals
- Avoiding high fat foods
- Avoiding sugary foods
- Staying upright after eating
Over-the-Counter Options:
- Anti-emetics: Pepto-Bismol
Diarrhea
Non-medication related tips:
- Increasing soluble fiber
- Beans
- Oats
- Peas
- Apples
- Pears
- Carrots
Over-the-Counter Options:
- Bulk-forming agents: Imodium
- Fiber supplements: Benefiber, Metamucil
Constipation
Non-medication related tips:
- Drinking more water
- Increasing soluble fiber (as above)
- Increasing insoluble fiber
- Wheat
- Nuts
- Beans
- Cauliflower
- Green beans
- Potatoes
- Avocados
Over-the-Counter Options:
- Laxatives: Magnesium Citrate, Miralax
- Fiber supplements: Metamucil
How can Preston's Pharmacy help?
Preston’s Pharmacy offers semaglutide injections in combination to B6. Vitamin B6 is used in order to mitigate GI upsets that can be caused by semaglutide injections. Preston’s Pharmacy uses vitamin B6 because it treats GI symptoms better than other B vitamins.
Preston’s Pharmacy offers Semaglutide-B6 in 2.5-2.5mg/mL concentrations. Call a pharmacist today to order a 2mL vial for a competitive price of $250.
If you are looking for a competitive alternative to Mounjaro, Preston’s Pharmacy offers Tirzepatide-B6 in 10-2.5mg/mL concentrations. Call a pharmacist today to order a 2mL vial for a competitive price of $350.